The role of magnesium in nucleic-acid and protein metabolism.

Magnesium is an essential cofactor for the synthesis and salvage of purine and pyrimidine nucleotides. It plays important roles in the structure of nucleic acids and affects their interaction with proteins and other ligands. Magnesium is required for DNA replication, transcription into RNA and translation into protein. In spite of the diverse roles of magnesium in these fundamental processes, metabolic regulation by magnesium has not been observed. Its role in the regulation of cell growth, division and differentiation remains uncertain.

 

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Magnesium And Digestion

Magnesium plays a critical role in healthy digestion. It acts as a coenzyme, and one of the places where enzymes and their coenzymes work their hardest is in your digestive system. It is these enzymes that help in the digestion in all of the food that your eat and they could not do what they do this without important coenzymes like magnesium.

Magnesium along with ATP helps your stomach manufacture hydrochloric acid to break down your foods. It also plays a critical role in the production of bile from your liver. And it is the bile that aids in the digestion of fats and cholesterol. This process too depends on magnesium. Without enough magnesium, you would suffer from terrible spastic constipation.

Your body also requires magnesium to begin the synthesis of RNA and DNA in the digestive system. Magnesium works with the pancreatic enzyme, deoxyribonuclease to break down DNA molecules from your food into nucleotides. These nucleotides are then absorbed through your intestine into your cells to be used in the synthesis of new RNA and DNA.

Magnesium in high doses also works great as a laxative. Since magnesium helps muscles to relax, it can help your intestines to relax which, if taken in large doses can result in loose stool. Many choose to help to alleviate constipation by supplementing additional magnesium to their diet.